AskDefine | Define microcephalic

Dictionary Definition

microcephalic adj : having an abnormally small head and underdeveloped brain; "a nanocephalic dwarf" [syn: microcephalous, nanocephalic]

User Contributed Dictionary



  1. Having an abnormally small head


  1. A microcephalic person

Related terms

Extensive Definition

Microcephaly is a neurological disorder in which the circumference of the head is significantly smaller than average for the person's age and sex. Microcephaly may be congenital or it may develop in the first few years of life. The disorder may stem from a wide variety of conditions that cause abnormal growth of the brain, or from syndromes associated with chromosomal abnormalities. Two copies of a loss-of-function mutation in one of the microcephalin genes causes primary microcephaly.
Infants with microcephaly are born with either a normal or reduced head size. Subsequently the head fails to grow while the face continues to develop at a normal rate, producing a child with a small head and a receding forehead, and a loose, often wrinkled scalp. As the child grows older, the smallness of the skull becomes more obvious, although the entire body also is often underweight and dwarfed. Development of motor functions and speech may be delayed. Hyperactivity and mental retardation are common occurrences, although the degree of each varies. Convulsions may also occur. Motor ability varies, ranging from clumsiness in some to spastic quadriplegia in others.
Generally there is no specific treatment for microcephaly. Treatment is symptomatic and supportive.
In general, life expectancy for individuals with microcephaly is reduced and the prognosis for normal brain function is poor. The prognosis varies depending on the presence of associated abnormalities.


Microcephaly is a type of cephalic disorder. This is a disorder characterized by a small brain and may be caused by a disturbance in the proliferation of nerve cells. Microcephaly may also be associated with maternal problems such as alcoholism (which can result in the fetal alcohol syndrome disability), diabetes, or rubella (German measles). A genetic factor may play a role in causing some cases of microcephaly. Affected newborns generally have striking neurological defects and seizures. Severely impaired intellectual development is common, but disturbances in motor functions may not appear until later in life.

Famous microcephalics

microcephalic in Arabic: صعل
microcephalic in Czech: Mikrocefalie
microcephalic in German: Mikrozephalie
microcephalic in Spanish: Microcefalia
microcephalic in French: Microcéphalie
microcephalic in Latvian: Mikrocefālija
microcephalic in Dutch: Microcefalie
microcephalic in Polish: Mikrocefalia
microcephalic in Portuguese: Microcefalia
microcephalic in Russian: Микроцефалия
microcephalic in Finnish: Mikrokefalia
microcephalic in Swedish: Mikrocefali
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